Journal of Foot and Ankle Research
A severe case of erythrodermic psoriasis associated with advanced nail and joint manifestations
Carlos G Teran , Carlos N Teran-Escalera and Carola Balderrama
Journal of Medical Case Reports 2010, 4:179doi:10.1186/1752-1947-4-179 Published: 15 June 2010
Abstract (provisional)
Introduction Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in children and adults. Its systemic involvement and a diverse range of clinical findings in the joint and nails are commonly described. A high index of suspicion and an exhaustive differential diagnosis involving other causes of erythroderma should be initially considered.
Case presentation We present the case of a 9-year-old native Hispanic girl with severe erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations. Our patient showed an excellent response to methotrexate medication.
Conclusion This case shows clinical features not commonly described or reported in severe cases of erythrodermic psoriasis, including severe and rare nail and arthritic findings in a pediatric scenario.
Posted by Hylton Menz at 03:09 Comments (0)
Small cell osteosarcoma of a toe phalanx: a case report
Small cell osteosarcoma of a toe phalanx: a case report and review of literature
Journal of Orthopaedic Surgery and Research 2010, 5:36doi:10.1186/1749-799X-5-36
Abstract (provisional)
This report describes the radiological and histological findings of a small cell osteosarcoma of a toe phalanx in a 38 year old man. This man presented with pain, swelling and redness of the left third toe. Medical history revealed an osteomyelitis of this toe eight years prior. Based on clinical findings and medical history the lesion was diagnosed as an osteomyelitis. However, peroperatively the lesion had a malignant aspect. Histological examination revealed a small cell osteosarcoma of the proximal phalanx. Osteosarcoma of the foot and especially of the tubular bones is rare. Moreover small cell osteosarcoma is a rare subtype of osteosarcoma. This case demonstrates that medical history and clinical examination can be misleading. In patients with apparent bone destruction, a malignancy must always be excluded prior to treatment. It emphasises the care that should be taken in the process of formulating a diagnosis.
Posted by Hylton Menz at 03:42 Comments (0)