Cell & Bioscience Blog
Winners announced for the 2011 Ming K Jeang Award for Excellence in Cell & Bioscience
Our annual Ming K Jeang Award for Excellence in Cell & Bioscience, established this year, recognizes the excellence of research published in the journal in the past year. The following two winning articles, selected by a committee of internationally renowned Cell & Bioscience Editors, chaired by Dr Chris Lau, have been chosen for their innovation, high-quality execution and lasting contribution to the biosciences.
Shiwen Peng, Barbara Ma, Shu-Hsia Chen, Chien-Fu Hung, TC Wu
Cell & Bioscience 2011, 1:26 (28 July 2011)
Transient knockdown and overexpression reveal a developmental role for the zebrafish enosf1b gene
Steve Finckbeiner, Pin-Joe Ko, Blake Carrington, Raman Sood, Kenneth Gross, Bruce Dolnick, Janice Sufrin, Paul Liu
Cell & Bioscience 2011, 1:32 (26 September 2011)
Congratulations to the authors of the winning articles! We look forward receiving further outstanding research contributions this year and beyond.
Posted by Elizabeth Bal at 10:25 Comments (0)
DNA damage response and genome stability, a special issue from Cell & Bioscience
The maintenance of genomic integrity in response to DNA damage relies on the intricate coordination of DNA repair, cell cycle progression, transcriptional and post-transcriptional regulation and apoptosis. The DNA damage response pathways play a critical role in human health, as failure at any of these steps could lead to cancer and other diseases.
In a collection of reviews
published in Cell & Bioscience today,
guest edited by Dr Guo-Min Li, we attempt to define the most challenging questions concerning DNA damage response
and repair, and to provide an overview of the latest advances in the field.
This is one of a number of exciting special issues to be published in Cell & Bioscience this year. To keep up-to-date with the latest journal content, please do sign up for article alerts.
Posted by Elizabeth Bal at 16:52 Comments (0)
Ming K. Jeang Award for Excellence in Cell & Bioscience
Cell & Bioscience announces the establishment of the Ming K. Jeang Award for Excellence in Cell & Bioscience. The Award, consisting of $500 cash and a certificate, is funded by a generous donation from the Ming K. Jeang Foundation and intends to honor outstanding research papers published in Cell & Bioscience. All research articles published in Cell & Bioscience are qualified for consideration and a committee of editors will select two research articles published in the preceding year in Cell & Bioscience to receive the award.
Posted by Elizabeth Bal at 14:14 Comments (0)
The USCACA and NFCR are pleased to invite nominations for 2012 USCACA-NFCR Scholar Awards
The Awards will recognize four Chinese investigators on the
basis of significant contributions in Basic and Translational
Cancer Research.
The Awards will be presented in a ceremony during the Chinese Anti-Cancer Association biannual meeting to be held in Beijing, China, September 7-9, 2012.
Candidacy is open to all junior Chinese researchers who were trained in US and subsequently returned to China during the last two years, and are currently active in cancer research in China. Selection of the award winners will be made on the basis of the candidate's meritorious achievements in cancer research both during training in US and after returning to China. The winners will receive an Award Recognition Plaque and an honorarium of $1,000 US dollars.
Nominations may be made by a scientist and must be submitted via
e-mail attachments to
Dr.
Shi-Yuan Cheng , the Chair of Scholarship Selection Committee of USCACA at chengs@upmc.edu no later than 12:00 p.m. US Eastern Time on March 31,
2012.
The following materials must be submitted:
2. Candidate's curriculum vitae, including a complete list of his or her publications;
3. Outline of the candidate’s future research plan: not exceed one page;
4.
Supporting letters:
one from the US mentor and one from current director/chair/dean in China.
The deadline for nomination is March 31, 2012
A
shared goal of USCACA and NFCR is to expedite novel cancer drug development by
stimulating the translation of laboratory discoveries into novel cancer
treatments, fostering collaborations in clinical cancer drug development, and
sharing best practices and knowledge between China and the United States.
To learn more and to join USCACA, please visit: www.uscaca.org
To learn more about NFCR, please visit: www.nfcr.org
Posted by Elizabeth Bal at 14:10 Comments (0)
Encouraging the availability of supporting data
In an effort to promote transparency and reproducibility in research, Cell & Bioscience has joined a growing number of BioMed Central journals aiming to increase the availability of supporting data.
We have introduced a new standard article section for research articles and short reports, ‘Availability of supporting data’, in which authors are encouraged to deposit the data set(s) supporting the results reported in submitted manuscripts in a publicly-accessible data repository, when it is not possible to publish them as additional files.
This optional section has been introduced with the aim of allowing authors to more easily indicate where and how the data supporting the results of their research can be found online, providing a better link between journal articles and underlying data.
Posted by Elizabeth Bal at 13:50 Comments (0)
'Feed a cold, starve a tumor' – glucose deprivation as a therapy for TSC-related tumors
Tuberous Sclerosis Complex (TSC) is an autosomal dominant disorder, caused by mutation in one of the tumor-suppressor genes, TSC1 or TSC2. The condition is characterized by the formation of multiple non-malignant tumours throughout the brain and other vital organs of the body, and is prevalent in nearly one million people worldwide, with symptoms ranging from mild skin abnormalities to uncontrollable seizures and kidney failure.
In the latest research published in Cell &
Bioscience, Jiang et al. demonstrate
that the growth and cell proliferation of TSC-related tumors can be inhibited by 2-deoxyglucose (2-DG),
which restricts glucose metabolism. In stark contrast,
a “carb-free” diet fails to prove effective in reducing tumor growth and leads
to increased tumor size.
Csibi and Blenis, in a commentary published in BMC Biology, discuss these new findings and their therapeutic potential:
“Cancer therapy is increasingly shifting toward individualized therapeutic approaches based on the genetic abnormalities exhibited by transformed cells. Jiang et al. demonstrate that targeting glucose addiction is an effective approach for decreasing the growth of tumors driven by TSC mutations. Thus glucose addiction may prove to be the ‘Achilles’ heel’ for the treatment of TSC.”
This research raises questions as to the potential use of 2-DG in treating TSC-tumors, in light of whether the toxic effects of 2-DG can be minimised, and moreover whether this will translate into a therapeutic approach for other tumor types.
Posted by Elizabeth Bal at 15:13 Comments (0)
Cell & Bioscience - indexing update
We are happy to share the excellent news that in less than 6 months since its official launch, Cell & Bioscience has been accepted for indexing in Scopus and PubMed. We look forward to the journal making further progress.
Posted by Elizabeth Bal at 18:33 Comments (0)
Registration and Abstract submission (www.SCBAmeeting2011.org ) are now open for the 13th SCBA International Meeting in
Posted by Kuan-Teh Jeang at 19:38 Comments (0)
Registration and Abstract submission (www.SCBAmeeting2011.org ) are now open for the 13th SCBA International Meeting in Guangzhou, China, July 25-29, 2011. A significant number of oral presentations will be picked from submitted Abstracts. In addition to over 70 outstanding symposium sessions and more than 300 cutting-edge speakers (http://www.scbameeting2011.org/a30081.aspx ), the meeting will feature an Editor's/Publisher's session. We expect representatives from Nature, Science, Cell, the JBC, BMC, Cell & Bioscience, and others to attend this session. We have confirmation that Dr. Emilie Marcus (Editor-in-Chief, Cell) and Dr. Marty Fedor (Editor-in-Chief, the JBC) will personally come. Names of other journal representatives will be updated in due course. Come to the SCBA meeting "Bioscience for the 21st century: Emerging frontiers and evolving concepts" and meet and speak with journal editors as well as your friends and colleagues.
Posted by Kuan-Teh Jeang at 19:31 Comments (0)
Ming K. Jeang scholarship Award for students and postdocs at the 13th SCBA Biennial Meeting
SCBA announces student and postdoc scholarship awards for participants at the 13th SCBA Biennial Meeting. The Ming K. Jeang Scholarship Awards are funded by a generous donation from the Ming K. Jeang Foundation and are open to selected students and postdoctoral fellows presenting at the meeting. To qualify, the applicants should have registered for the meeting and submitted an abstract online, and should then email a brief note expressing interest to apply, together with the submitted abstract to 'Lucia Liu' <xxlucia@yahoo.com.cn> by APRIL 15, 2011.
The abstracts will be reviewed by a committee and awardees will be announced at the meeting. Each awardee will receive an award certificate and a cash award of 800 Yuan. Up to 80 awards will be made to selected candidates. The scholarship award is open for competition by any students or postdocs, regardless of geographic origin, who has registered for and submitted an abstract for presentation at the meeting.
Posted by Elizabeth Bal at 10:53 Comments (0)
Senior Investigator and Head
Humoral Immunology Section, VRC
(Deadline: February 1)
The Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) is seeking an outstanding candidate to head the newly established Humoral Immunology Section, within the Virology Laboratory, located at Building 40, 40 Convent Drive, main NIH campus, Bethesda, Maryland. This new section will closely interact with the Virology Laboratory Section, the Structural Biology Section, the BSL-3 Virology Section, and the Structural BioInformatics Section, all located within the Virology Laboratory. All these laboratories support the VRC mission objectives of developing an HIV-1 vaccine candidate that elicits neutralizing antibodies to circulating viral isolates, and advancing such a vaccine into clinical trials. The Chief of the Humoral Immunology Section will exercise scientific leadership and be responsible for evaluating basic research vaccine strategies to elicit antibodies that neutralize HIV, and for studying antibody-mediated protective immune responses against HIV-1.
Specifically, the Chief of the Humoral Immunology Section will be responsible for conducting independent intramural research on understanding antibody-mediated protective immune responses against HIV-1 via studies of both the plasma antibody compartment and the B-cell compartment. He/she will be responsible for conducting top-tier independent research to define structural and functional mechanisms of Env neutralization, and to evaluate antibody responses from natural disease infection and from preclinical and clinical vaccine studies. It is expected that research conducted by this Senior Investigator will serve as a critical basis for development of tangible products for prevention of HIV-1 infection. The incumbent will serve as a member of the VRC Principal Investigator group which advises the VRC Director regarding scientific progress, and future scientific directions including design, planning and execution of basic, translational and clinical research. The Chief of the Humoral Immunology Section will have independent resources to carry out the research activities described above, as appropriate.
The qualified candidate will have an M.D., or Ph.D., and should be an acknowledged authority and expert in humoral immunology and HIV vaccine development. In addition the selected individual will have demonstrated proven ability to independently carry out a strong independent research program. The selected individual will also be expected to contribute to and provide oversight of collaborative basic, translational and clinical research, involving or based upon vaccine strategies intended to elicit antibodies that neutralize HIV, or to study antibody-mediated protective immune responses against HIV-1.
Salary will be based on the individual’s qualifications and experience. To apply for the position, interested candidates should submit their curriculum vitae, bibliography, a detailed statement of how your expertise can contribute to the success of the mission goals of the Humoral Immunology Section along with three letters of reference to: National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Attn: Bryan McClelland Building 40, Room 1100; 40 Convent Drive; Bethesda, MD 20892-3013 or email to mcclellb@niaid.nih.gov by February 1, 2011. Interested candidates may contact Dr. Richard Koup, Chair, NIAID Search Committee, at rkoup@niaid.nih.gov for further information. Further information regarding VRC laboratories is available at www.niaid.nih.gov/about/organization/vrc/Pages/default.aspx. DHHS and NIH are Equal Opportunity Employers.
Scientific Director
Division of Intramural Research, NICHD
(Deadline: February 15)
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (HHS), seeks to identify an outstanding Scientific Director to lead its Division of Intramural Research (DIR), located in Bethesda, Maryland. The NICHD Scientific Director leads a basic and clinical research program directed toward developing a greater understanding of the biological, medical, reproductive and behavioral aspects of normal and abnormal human development. The NICHD’s current research emphasis is on the cellular and molecular developmental mechanisms and interactions that guide a single fertilized egg cell through its development into a multi-cellular, highly organized and specialized adult organism.
This position offers a unique and exciting opportunity for an extremely capable individual to develop and implement an overall vision for the NICHD/DIR and to plan and oversee basic fundamental, clinical and applied research programs. The Scientific Director will evaluate research efforts and establish program priorities, allocate resources, direct training of pre-doctoral and post-doctoral fellows, collaborate with other NIH programs, and advise the NICHD Director and senior staff on DIR programs and on areas of scientific interest to the Institute. The incumbent plays a key role in creating and maintaining a nurturing research environment that encourages creativity, collaboration among scientists from different disciplines, effective training of post-doctoral fellows, and efficient utilization of resources. The DIR has a staff of approximately 1,200 and a current annual budget in excess of $185 million. In addition to the managerial/administrative responsibilities outlined above, the Scientific Director is expected to carry out his/her own high quality research program. Resources commensurate with the proposed program will be provided.
QUALIFICATIONS: Applicants must possess an M.D., Ph.D., or equivalent degree, and have demonstrated scientific leadership and/or senior-level research experience in a basic and/or clinical research program of national and international standing in an area relevant to maternal and child health or human development. The successful candidate will have a compelling vision for the future of the field, proven experience in managing and directing a scientific research program, and well-honed administrative and interpersonal skills. The NICHD seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to maintain the DIR’s research efforts at the forefront of science.
SALARY/BENEFITS: Salary is competitive and will be commensurate with the experience of the candidate. A full package of Federal Civil Service benefits is available, including: retirement, health and life insurance, long term care insurance, leave, and a Thrift Savings Plan (401K equivalent). The successful candidate is subject to a background investigation and financial disclosure requirements.
HOW TO APPLY: Interested candidates should submit a letter of interest, including a brief description of research and administrative experience; curriculum vitae and bibliography; and full contact information of five references. Application packages should be sent via e-mail to Mr. Michael Rosenthal at: rosentm@mail.nih.gov. Applications should be received by February 15, 2011. HHS and NIH are Equal Opportunity Employers
Senior Investigator
Division of Intramural Research, NIDA
(Deadline: February 25)
The Intramural Research Program (IRP), National Institute of Drug Abuse (NIDA), a research component of the National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is seeking an outstanding and internationally recognized senior scientist to initiate a multidisciplinary cognitive neuroscience program aimed at determining the behavioral, cognitive, and physiological mechanisms of substance use, abuse and addiction. The successful candidate must possess a Ph.D., M.D., or D.O. degree and have an outstanding publication record in cognitive neuroscience and substance abuse. In view of the required integrative approach, the successful candidate will be expected to collaborate with other research groups within NIDA and NIH - a proven ability to establish and sustain collaborative work is highly desirable. Candidates must submit a CV, a statement of proposed research objectives and goals (3 pages or less), 4 letters of recommendation (from non-collaborators) to: Joshua Kysiak, Intramural Program Specialist, NIDA IRP, 251 Bayview Boulevard, Suite 200, Room 04A524, Baltimore, Maryland 21224. Telephone 443-740-2465, FAX 443-740-2865, Email: kysiakjo@nida.nih.gov. Application materials must be received by close of business on February 25, 2011; late applications will not be considered. DHHS and NIH are Equal Opportunity Employers.
Scientific Director
Division of Intramural Research, NIEHS
(Deadline: February 28)
The National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health is seeking exceptional candidates for the position of Scientific Director for its Division of Intramural Research (DIR). The Scientific Director sets the priorities of the intramural research program and advises the Director on the scientific direction of the NIEHS. The NIEHS supports and conducts research to understand biological and chemical processes and the contribution of environmental agents to human disease and dysfunction, including mechanisms of environmentally associated diseases (www.niehs.nih.gov). Areas of research include but are not limited to Molecular Pharmacology and Toxicology, Molecular Genetics, Structural Biology, Signal Transduction, Neurobiology, Molecular Carcinogenesis, Reproductive and Developmental Toxicology, Comparative Medicine, Epidemiology, Respiratory Biology, Biostatistics and Clinical Research. This position offers a unique and exciting opportunity for an extremely capable leader to plan and oversee basic and applied research programs, evaluate research efforts, establish program priorities, allocate resources, direct training of pre-and post-doctoral fellows, collaborate with other NIH programs, foster interdisciplinary synergistic biomedical research, and advise the NIEHS Director and senior staff on the DIR and areas of science of interest to the Institute. The DIR is organized into four scientific programs including 12 laboratories and branches conducting laboratory, clinical, and population-based research. The Intramural Division has a staff of approximately 800 employees with an annual budget of approximately $110M. The selected candidate may have a modest independent research program if funds and space are available.
The NIEHS seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to lead a dynamic and diverse research program. Applicants must have a MD, PhD or equivalent degree and should have demonstrated scientific leadership and extensive scientific accomplishments including a research program of national and international standing in an area relevant to environmental health. Salary is commensurate with level of experience and accomplishments.
Interested candidates should send a cover letter including a brief description of research and administrative experience, a one-page vision statement for leading the DIR, curriculum vitae with bibliography, and full contact information for three to five individuals who may be contacted to provide letters of reference to: Ms. Stephanie Jones (DIR-11-01), Office of Human Resources, NIH, PO Box 12233,(MD K1-01), Research Triangle Park, NC 27709; or via email to collinsonj@od.nih.gov by February 28, 2011. DHHS and NIH are Equal Opportunity Employers. We are dedicated to building a diverse community in our training and employment programs.
Biostatistician for Gulf Oil Spill Study
Biostatistics Branch, NIEHS
(Deadline: March 1*)
The Biostatistics Branch is seeking a Staff Scientist with a strong background in biostatistics and a lively interest in methods and epidemiologic applications to participate in team-oriented research on a large prospective study of clean-up workers exposed to petroleum products, chemicals and other environmental hazards following the BP/Deepwater Horizon oil spill in the Gulf of Mexico. The position is ideal for a person with proven experience in applications to environmental epidemiology and interest in working collaboratively to assess potential human health effects of this recent environmental disaster. This project is directed by Dr. Dale Sandler, Principal Investigator and Chief of the Epidemiology Branch at the NIEHS. The NIEHS is part of NIH and is located in the Research Triangle area of North Carolina. The position offers opportunities for collaboration with other ongoing projects in biostatistics and epidemiology and will include time and support for carrying out investigator-initiated methodology research related to inference in epidemiologic studies.
Minimum qualifications include a doctoral degree (Ph.D. or equivalent) with a strong background in biostatistics and documented interest in epidemiology. Familiarity with methods for exposure assessment and modeling in the context of longitudinal studies is desirable. Salary is commensurate with background. Staff scientist positions within the NIH system are equivalent to research assistant professor positions in academia. The initial appointment is from 1 to 5 years and may be renewed after 5 years depending upon performance and need.
For additional information concerning the position, contact the Biostatistics Branch Chief,
Dr. Clarice Weinberg, at weinber2@niehs.nih.gov, or phone 919-541-4927. For information concerning biostatistics and epidemiology branch research projects and publications, see http://www.niehs.nih.gov/research/atniehs/labs/bb/index.cfm or www.niehs.nih.gov/epi.
Applications from women and minorities are particularly encouraged. Applications will be reviewed after March 1, 2011, but the position will remain open until filled. To apply, submit a cover letter indicating your research interests and experience, curriculum vitae and three letters of recommendation to: Ms. Emily Starnes (Vacancy Number DIR 11-02); Intramural Program Specialist; National Institutes of Health; National Institute of Environmental Health Sciences; P.O. Box 12233, Mail drop A2-06; 111 T.W. Alexander Drive, Room A252; Research Triangle Park, NC 27709; or e-mail: dir-appls@niehs.nih.gov. DHHS and NIH are Equal Opportunity Employers. We are dedicated to building a diverse community in our training and employment programs.
*An asterisk next to the closing date in the postings above indicates that applications will continue to be accepted and considered until the position is filled.
Statistician, Tenure or Tenure-Track
Radiation Epidemiology Branch, DCEG-NCI
(Deadline: April 15)
The Radiation Epidemiology Branch (REB, http://dceg.cancer.gov/reb, Chief, Dr. Martha Linet), a component of NCI’s intramural Division of Cancer Epidemiology and Genetics (DCEG), is recruiting a statistician to develop an independent research program focusing on development of statistical models that incorporate dose uncertainties, that provide cancer risk projections for low-dose exposures, that can be used to estimate radiation-induced lifetime risks, that quantify the effect of key modifiers on radiation-related cancer risks, or that provide mathematical formulations of biological models for radiation carcinogenesis.
Current REB research includes studies of late effects of radiological diagnostic examinations, radiotherapy, occupational exposures, or nuclear fallout from above-ground tests, military sources (Japanese atomic bomb survivors) or radiation accidents (Chernobyl). REB is also evaluating late health effects of new radiation technologies in medicine including the estimation of doses, extremely low-frequency and radio-frequency electromagnetic field exposures, and ultraviolet radiation. In addition, REB studies are examining gene-radiation interaction in studies of breast and thyroid cancer, etiologic and genetic studies (including genome-wide association studies) of brain tumors and thyroid cancer, and the development of various strategies for reconstructing historical radiation doses of medical radiation workers and populations exposed to environmental, military, and accidental sources of radiation exposure. Challenges for the statistician include modeling the excess relative and absolute risk as a function of dose, evaluating the modifying effects of dose-rate and type of radiation, addressing effects on risk estimates of uncertainties from complex dosimetry systems, developing appropriate analytic approaches for special study designs, identifying and describing gene-environment interaction, and developing strategies to identify true associations in genome-wide scans for disease-producing genetic variants. REB investigators are encouraged to collaborate with scientists in other parts of the DCEG, including members of the Biostatistics Branch and the Human Genetics Program.
Candidates must have a doctorate in biostatistics, statistics, mathematics or a related discipline (with additional post-doctoral experience in statistics). They must have at least two years of post-doctoral research experience and an established record of publications that demonstrates their ability to apply cutting edge, appropriate statistical models and analyze and interpret data from radiation epidemiology studies. They should also have knowledge of and demonstrated capacity to apply state-of-the-art statistical and epidemiologic methods in at least one of the following areas of research: risk assessment, measurement (dosimetry) errors, genetic susceptibility in relation to radiation carcinogenesis, or mechanisms of radiation carcinogenesis. Collaboration with epidemiologists, dosimetrists, health or medical physicists, radiologists, and laboratory investigators is central to the success of our research. Candidates must document the strong verbal and written communication skills that will be required to write effective research papers, present work at scientific meetings, and convey information clearly to staff, collaborators, consultants and contractors. Candidates must also be sufficiently experienced to function independently, both in the development of their own research efforts and in the mentoring and supervision of less experienced investigators. Appropriate office space and resources will be provided.
Salary is competitive and commensurate with research experience and accomplishments, and a full Civil Service package of benefits (including retirement, health insurance, life insurance, and a thrift savings plan) is available. Candidates may be eligible for the NIH Loan Repayment Program (http://www.LRP.NIH.gov). This position is not restricted to U.S. citizens. Interested individuals should send a cover letter, curriculum vitae, brief summary of research interests, experience and future plans, copies of no more than 5 selected publications and three letters of reference to: Ms. Judy Schwadron; Division of Cancer Epidemiology and Genetics; National Cancer Institute; 6120 Executive Blvd., Room EPS 8073; Rockville, MD 20852-7242; or e-mail: schwadrj@mail.nih.gov. The closing date of the advertisement is April 15, 2011. A completed package of your application is required in order to be considered for this position. DHHS and NIH are Equal Opportunity Employers.
Staff Scientist
Neuro-Oncology Branch, NCI
(Deadline: open-ended)
The Neuro-Oncology Branch, a trans-Institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health, is recruiting a Staff Scientist to work in the area of stem cell and/or cancer stem cell genomics and biology. Laboratory projects include the molecular and genetic study of primary glial neoplasms and neural and glioma stem cells for the purpose of identifying stem cell associated signal transduction mechanisms responsible for stem cell self renewal, proliferation, and differentiation. The successful candidate should have a M.D. or Ph.D. degree and at least 3 years of post-doctoral training in molecular and cellular biology. Experience in cancer and/or stem cell biology would be desirable.
Please send curriculum vitae, statement of research interests, and two letters of reference to: Howard A. Fine; Chief
Neuro-Oncology Branch, National Cancer Institute; 9030 Old Georgetown Rd., Rm. 225; Bethesda, MD 20892; or smithj9@mail.nih.gov. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute, and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.
Staff Clinician
CC and NHGRI Office of Rare Diseases
(Deadline: open-ended)
The NIH is seeking a general internist for a joint appointment in the Internal Medicine Consult Service (IMCS) of the Clinical Center (CC) and the Undiagnosed Diseases Program (UDP), Office of Rare Diseases, National Human Genome Research Institute and the Clinical Center. The Internal Medicine Consult Service provides advice and management for adult patients admitted to specialty services at the NIH Clinical Center. The Undiagnosed Diseases Program (UDP) is a trans-NIH initiative whose goals are to provide answers to patients with mysterious conditions that have long eluded diagnosis and to advance medical knowledge about rare and common diseases. As a physician for this program, the internist will have the opportunity to capitalize on resources at the nation’s largest hospital devoted entirely to research.
As part of this joint program, the internist will consult with patients presenting symptoms of unknown disorders. The overall purpose of the consultations is to determine a diagnosis and/or a possible therapeutic intervention. The internist will be a key member of a collaborative team, which includes several senior attending physicians who participate in the program’s clinical research. The candidate must have an M.D. or M.D/Ph.D. degree and be board certified in internal medicine or family practice, with considerable experience. Clinical expertise in the care of patients with genetic disorders and a strong interest in research are preferred. Curriculum vitae, bibliography, three letters of reference, and selected publications should be submitted to Dr. Fred Gill at: 10 Center Drive, Building 10 (CRC), 2-2731, MSC 1517, Bethesda, MD 20892. Phone: 301 496 9397, e-mail FGill@cc.nih.gov. Salary is based on relevant experience and education. DHHS and NIH are Equal Opportunity Employers and encourage applications from women and minorities.
Tenure Track Position
Office of the Scientific Director, NEI
(Deadline: open-ended)
The National Eye Institute (NEI), Office of the Scientific Director, seeks an outstanding clinician-scientist for a tenure-track position to develop an independent translational research program with focus on retinal diseases. The candidate will examine and treat patients with ophthalmic disease, and conduct clinical trials. NEI has particular interest in clinical research related to neuronal-glial interactions in retinal diseases and to genetic retinal degenerative diseases. The candidate must hold an M.D. or M.D./Ph.D. degree from a school in the US or Canada, or an equivalent degree from a foreign medical school. Candidates must be Board-certified by the American Board of Ophthalmology or Board-eligible and are expected to have completed post-residency fellowship training in Medical or Surgical Retina.
Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). This position will remain open until filled. Interested applicants should submit an electronic application including curriculum vitae, a detailed statement of the proposed research, copies of their five most significant publications, and three reference letters to Ms. Mica Gordon at gordonmi@nei.nih.gov. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor.
DHHS and NIH are Equal Opportunity Employers. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.
Research Scientist
Laboratory of Sensorimotor Research, NEI
(Deadline: open-ended)
The intramural program of the National Eye Institute invites applications for a position as a research scientist within the Laboratory of Sensorimotor Research. This position may be either tenured, or tenure track with conversion to tenure anytime within six years. Applicants will be expected to establish an independent research program related to understanding the neurobiology of the visual and/or oculomotor system.
The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements and visual perception. It has excellent facilities for the study of these systems in awake behaving primates, including dedicated computer systems, a machine shop, an electronics shop, and a histology lab. The Laboratory also provides the opportunity to collaborate on studies of human patients with diseases related to the visual and oculomotor systems. Although the Laboratory of Sensorimotor Research has historically studied primates, scientists using other species to study systems-level organization in ways not currently possible in primates will also are considered. Applicants should have a PhD or an MD/PhD and an outstanding record of accomplishments in visual or visuomotor systems neuroscience. This position will remain open until filled. Candidates should send a brief cover letter, curriculum vitae, bibliography, a one- or two-page statement of current research interests, copies of five recent, relevant publications, and three letters of recommendation to Okihide Hikosaka, Search Committee Chair, Building 49, Room 2A50, NIH, Bethesda, MD 20892-4435. DHHS and NIH are Equal Opportunity Employers.
Systems Biology/Bioinformatics Staff Scientist
Neuro-Oncology Branch, NCI-NINDS
(Deadline: open-ended)
The Neuro-Oncology Branch, a trans-institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health is seeking an outstanding candidate to work in the area of cancer genomics, bioinformatics and systems biology, particularly on computational modeling of signaling and gene networks in cancer cells. Ongoing projects include the integration of -omics and clinical data in the exploration of signaling and transcriptional networks that govern cell differentiation, proliferation and migration in primary brain tumors, cancer tumor stem cells and normal embryonic neural stem cells and the translation of those discoveries to patients through the highly integrated clinical brain tumor research program. Applicants should have a strong background in mathematical and computational modeling and be expected to carry out an interdisciplinary project with experimental groups.
The Staff Scientist candidate will take a lead role in the mentorship and scientific management of a team of bioinformatics research fellows. The following skills and qualifications are required: 1) PhD in computer science, mathematics, bioinformatics, or related fields, and at least 3 years of post-doctoral training in bioinformatics and/or systems biology; 2) experience in machine learning and network generation algorithms; 3) basic knowledge of cell/molecular biology; 4) experience in genome-wide genetic and gene expression data analysis.
Please send curriculum vitae, statement of research interests and two letters of reference to: Howard A. Fine, Chief; Neuro-Oncology Branch, National Cancer Institute; MSC 8200, Room 225; 9030 Old Georgetown Road; Bethesda, MD 20892-8200 or to smithj9@mail.nih.gov. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.
Chief
Laboratory of Computational Medicine, NEI
(Deadline: open-ended)
The NEI seeks to develop a new program in computational analysis that fully employs human genomic, transcriptomic, proteomic, metabolomic, neurophysiological and clinical data sets to reconstruct biological networks characteristic of normal and disease states. The magnitude, diversity, rich information content, and hierarchical connectivity of these data sets require the utilization and development of novel quantitative tools. The goal is to understand human disease at a molecular level in order to develop mechanism-based therapeutic interventions.
We invite applications for head of a new laboratory of Computational Medicine within the NEI Intramural Research Program. This initiative seeks to integrate and translate knowledge from genetics and biology to a wide range of disease processes using systems, network, statistical and bioinformatics approaches.
* Examples in ocular biology amenable to a systems approach would include neuro-immune interactions, gene regulatory networks during disease pathogenesis, protein interaction pathways, neuron-glial-vascular biological networks in the retina, neuronal networks in the CNS, and developmental conditions and disorders.
* The research program has interest in developing novel computational methodologies for analyzing large genetic, biological, biomedical, neuronal, and functional data sets. Particular attention will be paid to genotype-phenotype correlations, gene-gene and gene-environment interactions. In parallel, we will actively seek to develop disease intermediate phenotypes that reflect the underlying biology and pathophysiology of disease.
* Data sets from large clinical trials, genetic studies (including GWAS), expression profiling in normal and disease conditions, and from the eyeGENE human research repository for monogenic ophthalmic diseases will be developed to reconstruct and understand ocular biological networks that link genetic perturbations, small molecule interactions, and physiological processes, to predict normal and disease states
The NEI/NIH provides an exceptional environment of dedicated scientists as well as a wide range of resources. We currently envision that this program will be located in the newly constructed Porter Neuroscience complex that houses a diverse set of investigators from many different Institutes. The successful candidate will be expected to recruit tenure-track faculty in areas that may include computational medicine or neuroscience, network biology, genetic or molecular epidemiology, cell and molecular biology, statistical genetics, bioinformatics, and biostatistics into the new Laboratory of Computational Medicine. Applicants should have a MD, MD/PhD or PhD and an outstanding record of accomplishments in genetics, epidemiology, neuroscience, cell and molecular biology, biostatistics, or a related quantitative discipline. Senior scientists would have the opportunity to maintain their participation in existing collaborative research in non-eye diseases if desired.
This position will remain open until filled. Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments, names of three references, and a detailed experimental plan for the development of this program. These materials should be sent to: The Office of the Scientific Director, National Eye Institute, Attention: Ms. Mica Gordon (gordonmi@nei.nih.gov), NIH Building 31, 31 Center Drive, Room 6A22, Bethesda, MD, 20892. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor. DHHS and NIH are Equal Opportunity Employers.
Chief, Visuomotor Disorders Section
Laboratory of Sensorimotor Research, NEI
(Deadline: open-ended)
The National Eye Institute (NEI) seeks an outstanding clinician scientist for a tenured or tenure-track position as Chief, Visuomotor Disorders Section in the Laboratory of Sensorimotor Research (LSR) in the Division of Intramural Research. This recruitment is directed towards clinicians with expertise in central disorders that affect vision and/or eye movements (including disorders of binocular function). The post offers a unique opportunity for a talented individual to provide strong and stimulating leadership in an organization dedicated to uncovering new scientific knowledge, both laboratory and clinical. We welcome the full range of candidates at all levels.
The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements, visual perception and their disorders. The Visuomotor Disorders Section Chief is expected to create a vigorous research program dedicated to elucidating the role played by these brain mechanisms in human disease, and to explore treatments. The Chief will develop broad investigational plans, independently and in collaboration with other NEI investigators and research scientists in the United States and abroad. The Chief will examine and treat patients, as well as design, implement and conduct research and clinical protocols. An opportunity exists for the Section Chief to recruit staff and supervise training. The NEI provides an exceptional environment for clinical research including the infrastructure necessary for patient recruitment, a clinical protocol development group, and a Contract Research Organization that provides statistical and epidemiological expertise, data management and analysis, study monitoring, regulatory guidance, and overall operational support. The NIH Clinical Center provides additional access to exceptionally broad medical and diagnostic resources. In addition, the LSR provides exceptional support for more specialized needs, such as the measurement of eye movements and computational analysis/modeling.
The position requires an ability to integrate basic, clinical and translational research, and create an intellectual synergy and an environment for state-of-the art patient care for those suffering from visual dysfunction. At a minimum, candidates should have a Doctor of Medicine degree from a school in the U.S. or Canada approved by a recognized accrediting body in the year of the applicant's graduation, or a Doctor of Medicine or equivalent degree from a foreign medical school which provided education and medical knowledge substantially equivalent to accredited schools in the United States. Candidates should be Board-certified, board eligible or equivalent, have direct clinical experience. Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments and three reference letters. Applicants should also submit a written statement with their perspective on the needs and opportunities necessary to move from the basic understanding of brain mechanisms supporting vision and eye movements to clinical therapeutic interventions and improved patient care. This statement should indicate how the applicant's particular expertise and background could contribute to this transition. Applications should be sent to: Mica Gordon, Executive Assistant, Office of the Scientific Director, National Eye Institute, Building 31, Room 6A22, 31 Center Drive, Bethesda, MD 20892; Tel: 301-451-6763, Email: gordonmi@nei.nih.gov. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.
Posted by Kuan-Teh Jeang at 13:10 Comments (0)
NIH Lasker Clinical Research Scholars Positions Open
The NIH has launched a new program in conjunction with the Lasker Foundation to support clinical researchers for upwards of 12 years. The goal is to bridge the widening gap between cutting-edge research and improved patient care.
The initiative, called the Lasker Clinical Research Scholars Program, represents an historic partnership between the NIH intramural and extramural research programs. The program enables exceptional clinical researchers in the early stages of their careers to first spend 5 to 7 years as investigators in the NIH intramural research program. Upon successful completion of this first stage, the scholars would be offered the opportunity to remain at the NIH as senior clinical research scientists or to apply for up to 5 years of independent financial support at a university or other external research institution.
The program is open to clinician scientists both from the extramural and the intramural community. Applicants must have an MD, MD/PhD, DO, DDS, DMD, RN/PhD or equivalent clinical degree, and must be no more than 6 years from completion of their core residency training program. The deadline is March 4, 2011, for a letter of intent, and April 4, 2011, for the full application. Candidates must also obtain a DUNS number and register with the NIH eRA Commons prior to submitting an application.
More information, including the RFA, is at http://www.nih.gov/science/laskerscholar. Direct any questions about this program to Charles R. Dearolf, Ph.D., Assistant Director for Intramural Research, at LaskerScholar@nih.gov.
Posted by Kuan-Teh Jeang at 13:04 Comments (0)
Scientific Director
Division of Intramural Research, NICHD
(Deadline: February 15)
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (HHS), seeks to identify an outstanding Scientific Director to lead its Division of Intramural Research (DIR), located in Bethesda, Maryland. The NICHD Scientific Director leads a basic and clinical research program directed toward developing a greater understanding of the biological, medical, reproductive and behavioral aspects of normal and abnormal human development. The NICHD’s current research emphasis is on the cellular and molecular developmental mechanisms and interactions that guide a single fertilized egg cell through its development into a multi-cellular, highly organized and specialized adult organism.
This position offers a unique and exciting opportunity for an extremely capable individual to develop and implement an overall vision for the NICHD/DIR and to plan and oversee basic fundamental, clinical and applied research programs. The Scientific Director will evaluate research efforts and establish program priorities, allocate resources, direct training of pre-doctoral and post-doctoral fellows, collaborate with other NIH programs, and advise the NICHD Director and senior staff on DIR programs and on areas of scientific interest to the Institute. The incumbent plays a key role in creating and maintaining a nurturing research environment that encourages creativity, collaboration among scientists from different disciplines, effective training of post-doctoral fellows, and efficient utilization of resources. The DIR has a staff of approximately 1,200 and a current annual budget in excess of $185 million. In addition to the managerial/administrative responsibilities outlined above, the Scientific Director is expected to carry out his/her own high quality research program. Resources commensurate with the proposed program will be provided.
QUALIFICATIONS: Applicants must possess an M.D., Ph.D., or equivalent degree, and have demonstrated scientific leadership and/or senior-level research experience in a basic and/or clinical research program of national and international standing in an area relevant to maternal and child health or human development. The successful candidate will have a compelling vision for the future of the field, proven experience in managing and directing a scientific research program, and well-honed administrative and interpersonal skills. The NICHD seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to maintain the DIR’s research efforts at the forefront of science.
SALARY/BENEFITS: Salary is competitive and will be commensurate with the experience of the candidate. A full package of Federal Civil Service benefits is available, including: retirement, health and life insurance, long term care insurance, leave, and a Thrift Savings Plan (401K equivalent). The successful candidate is subject to a background investigation and financial disclosure requirements.
HOW TO APPLY: Interested candidates should submit a letter of interest, including a brief description of research and administrative experience; curriculum vitae and bibliography; and full contact information of five references. Application packages should be sent via e-mail to Mr. Michael Rosenthal at: rosentm@mail.nih.gov. Applications should be received by February 15, 2011. HHS and NIH are Equal Opportunity Employers
Senior Investigator
Division of Intramural Research, NIDA
(Deadline: February 25)
The Intramural Research Program (IRP), National Institute of Drug Abuse (NIDA), a research component of the National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is seeking an outstanding and internationally recognized senior scientist to initiate a multidisciplinary cognitive neuroscience program aimed at determining the behavioral, cognitive, and physiological mechanisms of substance use, abuse and addiction. The successful candidate must possess a Ph.D., M.D., or D.O. degree and have an outstanding publication record in cognitive neuroscience and substance abuse. In view of the required integrative approach, the successful candidate will be expected to collaborate with other research groups within NIDA and NIH - a proven ability to establish and sustain collaborative work is highly desirable. Candidates must submit a CV, a statement of proposed research objectives and goals (3 pages or less), 4 letters of recommendation (from non-collaborators) to: Joshua Kysiak, Intramural Program Specialist, NIDA IRP, 251 Bayview Boulevard, Suite 200, Room 04A524, Baltimore, Maryland 21224. Telephone 443-740-2465, FAX 443-740-2865, Email: kysiakjo@nida.nih.gov. Application materials must be received by close of business on February 25, 2011; late applications will not be considered. DHHS and NIH are Equal Opportunity Employers.
Scientific Director
Division of Intramural Research, NIEHS
(Deadline: February 28)
The National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health is seeking exceptional candidates for the position of Scientific Director for its Division of Intramural Research (DIR). The Scientific Director sets the priorities of the intramural research program and advises the Director on the scientific direction of the NIEHS. The NIEHS supports and conducts research to understand biological and chemical processes and the contribution of environmental agents to human disease and dysfunction, including mechanisms of environmentally associated diseases (www.niehs.nih.gov). Areas of research include but are not limited to Molecular Pharmacology and Toxicology, Molecular Genetics, Structural Biology, Signal Transduction, Neurobiology, Molecular Carcinogenesis, Reproductive and Developmental Toxicology, Comparative Medicine, Epidemiology, Respiratory Biology, Biostatistics and Clinical Research. This position offers a unique and exciting opportunity for an extremely capable leader to plan and oversee basic and applied research programs, evaluate research efforts, establish program priorities, allocate resources, direct training of pre-and post-doctoral fellows, collaborate with other NIH programs, foster interdisciplinary synergistic biomedical research, and advise the NIEHS Director and senior staff on the DIR and areas of science of interest to the Institute. The DIR is organized into four scientific programs including 12 laboratories and branches conducting laboratory, clinical, and population-based research. The Intramural Division has a staff of approximately 800 employees with an annual budget of approximately $110M. The selected candidate may have a modest independent research program if funds and space are available.
The NIEHS seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to lead a dynamic and diverse research program. Applicants must have a MD, PhD or equivalent degree and should have demonstrated scientific leadership and extensive scientific accomplishments including a research program of national and international standing in an area relevant to environmental health. Salary is commensurate with level of experience and accomplishments.
Interested candidates should send a cover letter including a brief description of research and administrative experience, a one-page vision statement for leading the DIR, curriculum vitae with bibliography, and full contact information for three to five individuals who may be contacted to provide letters of reference to: Ms. Stephanie Jones (DIR-11-01), Office of Human Resources, NIH, PO Box 12233,(MD K1-01), Research Triangle Park, NC 27709; or via email to collinsonj@od.nih.gov by February 28, 2011. DHHS and NIH are Equal Opportunity Employers. We are dedicated to building a diverse community in our training and employment programs.
Biostatistician for Gulf Oil Spill Study
Biostatistics Branch, NIEHS
(Deadline: March 1*)
The Biostatistics Branch is seeking a Staff Scientist with a strong background in biostatistics and a lively interest in methods and epidemiologic applications to participate in team-oriented research on a large prospective study of clean-up workers exposed to petroleum products, chemicals and other environmental hazards following the BP/Deepwater Horizon oil spill in the Gulf of Mexico. The position is ideal for a person with proven experience in applications to environmental epidemiology and interest in working collaboratively to assess potential human health effects of this recent environmental disaster. This project is directed by Dr. Dale Sandler, Principal Investigator and Chief of the Epidemiology Branch at the NIEHS. The NIEHS is part of NIH and is located in the Research Triangle area of North Carolina. The position offers opportunities for collaboration with other ongoing projects in biostatistics and epidemiology and will include time and support for carrying out investigator-initiated methodology research related to inference in epidemiologic studies.
Minimum qualifications include a doctoral degree (Ph.D. or equivalent) with a strong background in biostatistics and documented interest in epidemiology. Familiarity with methods for exposure assessment and modeling in the context of longitudinal studies is desirable. Salary is commensurate with background. Staff scientist positions within the NIH system are equivalent to research assistant professor positions in academia. The initial appointment is from 1 to 5 years and may be renewed after 5 years depending upon performance and need.
For additional information concerning the position, contact the Biostatistics Branch Chief,
Dr. Clarice Weinberg, at weinber2@niehs.nih.gov, or phone 919-541-4927. For information concerning biostatistics and epidemiology branch research projects and publications, see http://www.niehs.nih.gov/research/atniehs/labs/bb/index.cfm or www.niehs.nih.gov/epi.
Applications from women and minorities are particularly encouraged. Applications will be reviewed after March 1, 2011, but the position will remain open until filled. To apply, submit a cover letter indicating your research interests and experience, curriculum vitae and three letters of recommendation to: Ms. Emily Starnes (Vacancy Number DIR 11-02); Intramural Program Specialist; National Institutes of Health; National Institute of Environmental Health Sciences; P.O. Box 12233, Mail drop A2-06; 111 T.W. Alexander Drive, Room A252; Research Triangle Park, NC 27709; or e-mail: dir-appls@niehs.nih.gov. DHHS and NIH are Equal Opportunity Employers. We are dedicated to building a diverse community in our training and employment programs.
*An asterisk next to the closing date in the postings above indicates that applications will continue to be accepted and considered until the position is filled. Statistician, Tenure or Tenure-Track
Radiation Epidemiology Branch, DCEG-NCI
(Deadline: April 15)
The Radiation Epidemiology Branch (REB, http://dceg.cancer.gov/reb, Chief, Dr. Martha Linet), a component of NCI’s intramural Division of Cancer Epidemiology and Genetics (DCEG), is recruiting a statistician to develop an independent research program focusing on development of statistical models that incorporate dose uncertainties, that provide cancer risk projections for low-dose exposures, that can be used to estimate radiation-induced lifetime risks, that quantify the effect of key modifiers on radiation-related cancer risks, or that provide mathematical formulations of biological models for radiation carcinogenesis.
Current REB research includes studies of late effects of radiological diagnostic examinations, radiotherapy, occupational exposures, or nuclear fallout from above-ground tests, military sources (Japanese atomic bomb survivors) or radiation accidents (Chernobyl). REB is also evaluating late health effects of new radiation technologies in medicine including the estimation of doses, extremely low-frequency and radio-frequency electromagnetic field exposures, and ultraviolet radiation. In addition, REB studies are examining gene-radiation interaction in studies of breast and thyroid cancer, etiologic and genetic studies (including genome-wide association studies) of brain tumors and thyroid cancer, and the development of various strategies for reconstructing historical radiation doses of medical radiation workers and populations exposed to environmental, military, and accidental sources of radiation exposure. Challenges for the statistician include modeling the excess relative and absolute risk as a function of dose, evaluating the modifying effects of dose-rate and type of radiation, addressing effects on risk estimates of uncertainties from complex dosimetry systems, developing appropriate analytic approaches for special study designs, identifying and describing gene-environment interaction, and developing strategies to identify true associations in genome-wide scans for disease-producing genetic variants. REB investigators are encouraged to collaborate with scientists in other parts of the DCEG, including members of the Biostatistics Branch and the Human Genetics Program.
Candidates must have a doctorate in biostatistics, statistics, mathematics or a related discipline (with additional post-doctoral experience in statistics). They must have at least two years of post-doctoral research experience and an established record of publications that demonstrates their ability to apply cutting edge, appropriate statistical models and analyze and interpret data from radiation epidemiology studies. They should also have knowledge of and demonstrated capacity to apply state-of-the-art statistical and epidemiologic methods in at least one of the following areas of research: risk assessment, measurement (dosimetry) errors, genetic susceptibility in relation to radiation carcinogenesis, or mechanisms of radiation carcinogenesis. Collaboration with epidemiologists, dosimetrists, health or medical physicists, radiologists, and laboratory investigators is central to the success of our research. Candidates must document the strong verbal and written communication skills that will be required to write effective research papers, present work at scientific meetings, and convey information clearly to staff, collaborators, consultants and contractors. Candidates must also be sufficiently experienced to function independently, both in the development of their own research efforts and in the mentoring and supervision of less experienced investigators. Appropriate office space and resources will be provided.
Salary is competitive and commensurate with research experience and accomplishments, and a full Civil Service package of benefits (including retirement, health insurance, life insurance, and a thrift savings plan) is available. Candidates may be eligible for the NIH Loan Repayment Program (http://www.LRP.NIH.gov). This position is not restricted to U.S. citizens. Interested individuals should send a cover letter, curriculum vitae, brief summary of research interests, experience and future plans, copies of no more than 5 selected publications and three letters of reference to: Ms. Judy Schwadron; Division of Cancer Epidemiology and Genetics; National Cancer Institute; 6120 Executive Blvd., Room EPS 8073; Rockville, MD 20852-7242; or e-mail: schwadrj@mail.nih.gov. The closing date of the advertisement is April 15, 2011. A completed package of your application is required in order to be considered for this position. DHHS and NIH are Equal Opportunity Employers.
Staff Scientist
Neuro-Oncology Branch, NCI
(Deadline: open-ended)
The Neuro-Oncology Branch, a trans-Institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health, is recruiting a Staff Scientist to work in the area of stem cell and/or cancer stem cell genomics and biology. Laboratory projects include the molecular and genetic study of primary glial neoplasms and neural and glioma stem cells for the purpose of identifying stem cell associated signal transduction mechanisms responsible for stem cell self renewal, proliferation, and differentiation. The successful candidate should have a M.D. or Ph.D. degree and at least 3 years of post-doctoral training in molecular and cellular biology. Experience in cancer and/or stem cell biology would be desirable.
Please send curriculum vitae, statement of research interests, and two letters of reference to: Howard A. Fine; Chief
Neuro-Oncology Branch, National Cancer Institute; 9030 Old Georgetown Rd., Rm. 225; Bethesda, MD 20892; or smithj9@mail.nih.gov. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute, and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.
Staff Clinician
CC and NHGRI Office of Rare Diseases
(Deadline: open-ended)
The NIH is seeking a general internist for a joint appointment in the Internal Medicine Consult Service (IMCS) of the Clinical Center (CC) and the Undiagnosed Diseases Program (UDP), Office of Rare Diseases, National Human Genome Research Institute and the Clinical Center. The Internal Medicine Consult Service provides advice and management for adult patients admitted to specialty services at the NIH Clinical Center. The Undiagnosed Diseases Program (UDP) is a trans-NIH initiative whose goals are to provide answers to patients with mysterious conditions that have long eluded diagnosis and to advance medical knowledge about rare and common diseases. As a physician for this program, the internist will have the opportunity to capitalize on resources at the nation’s largest hospital devoted entirely to research.
As part of this joint program, the internist will consult with patients presenting symptoms of unknown disorders. The overall purpose of the consultations is to determine a diagnosis and/or a possible therapeutic intervention. The internist will be a key member of a collaborative team, which includes several senior attending physicians who participate in the program’s clinical research. The candidate must have an M.D. or M.D/Ph.D. degree and be board certified in internal medicine or family practice, with considerable experience. Clinical expertise in the care of patients with genetic disorders and a strong interest in research are preferred. Curriculum vitae, bibliography, three letters of reference, and selected publications should be submitted to Dr. Fred Gill at: 10 Center Drive, Building 10 (CRC), 2-2731, MSC 1517, Bethesda, MD 20892. Phone: 301 496 9397, e-mail FGill@cc.nih.gov. Salary is based on relevant experience and education. DHHS and NIH are Equal Opportunity Employers and encourage applications from women and minorities.
Tenure Track Position
Office of the Scientific Director, NEI
(Deadline: open-ended)
The National Eye Institute (NEI), Office of the Scientific Director, seeks an outstanding clinician-scientist for a tenure-track position to develop an independent translational research program with focus on retinal diseases. The candidate will examine and treat patients with ophthalmic disease, and conduct clinical trials. NEI has particular interest in clinical research related to neuronal-glial interactions in retinal diseases and to genetic retinal degenerative diseases. The candidate must hold an M.D. or M.D./Ph.D. degree from a school in the US or Canada, or an equivalent degree from a foreign medical school. Candidates must be Board-certified by the American Board of Ophthalmology or Board-eligible and are expected to have completed post-residency fellowship training in Medical or Surgical Retina.
Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). This position will remain open until filled. Interested applicants should submit an electronic application including curriculum vitae, a detailed statement of the proposed research, copies of their five most significant publications, and three reference letters to Ms. Mica Gordon at gordonmi@nei.nih.gov. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor.
DHHS and NIH are Equal Opportunity Employers. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.
Research Scientist
Laboratory of Sensorimotor Research, NEI
(Deadline: open-ended)
The intramural program of the National Eye Institute invites applications for a position as a research scientist within the Laboratory of Sensorimotor Research. This position may be either tenured, or tenure track with conversion to tenure anytime within six years. Applicants will be expected to establish an independent research program related to understanding the neurobiology of the visual and/or oculomotor system.
The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements and visual perception. It has excellent facilities for the study of these systems in awake behaving primates, including dedicated computer systems, a machine shop, an electronics shop, and a histology lab. The Laboratory also provides the opportunity to collaborate on studies of human patients with diseases related to the visual and oculomotor systems. Although the Laboratory of Sensorimotor Research has historically studied primates, scientists using other species to study systems-level organization in ways not currently possible in primates will also are considered. Applicants should have a PhD or an MD/PhD and an outstanding record of accomplishments in visual or visuomotor systems neuroscience. This position will remain open until filled. Candidates should send a brief cover letter, curriculum vitae, bibliography, a one- or two-page statement of current research interests, copies of five recent, relevant publications, and three letters of recommendation to Okihide Hikosaka, Search Committee Chair, Building 49, Room 2A50, NIH, Bethesda, MD 20892-4435. DHHS and NIH are Equal Opportunity Employers.
Systems Biology/Bioinformatics Staff Scientist
Neuro-Oncology Branch, NCI-NINDS
(Deadline: open-ended)
The Neuro-Oncology Branch, a trans-institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health is seeking an outstanding candidate to work in the area of cancer genomics, bioinformatics and systems biology, particularly on computational modeling of signaling and gene networks in cancer cells. Ongoing projects include the integration of -omics and clinical data in the exploration of signaling and transcriptional networks that govern cell differentiation, proliferation and migration in primary brain tumors, cancer tumor stem cells and normal embryonic neural stem cells and the translation of those discoveries to patients through the highly integrated clinical brain tumor research program. Applicants should have a strong background in mathematical and computational modeling and be expected to carry out an interdisciplinary project with experimental groups.
The Staff Scientist candidate will take a lead role in the mentorship and scientific management of a team of bioinformatics research fellows. The following skills and qualifications are required: 1) PhD in computer science, mathematics, bioinformatics, or related fields, and at least 3 years of post-doctoral training in bioinformatics and/or systems biology; 2) experience in machine learning and network generation algorithms; 3) basic knowledge of cell/molecular biology; 4) experience in genome-wide genetic and gene expression data analysis.
Please send curriculum vitae, statement of research interests and two letters of reference to: Howard A. Fine, Chief; Neuro-Oncology Branch, National Cancer Institute; MSC 8200, Room 225; 9030 Old Georgetown Road; Bethesda, MD 20892-8200 or to smithj9@mail.nih.gov. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.
Chief
Laboratory of Computational Medicine, NEI
(Deadline: open-ended)
The NEI seeks to develop a new program in computational analysis that fully employs human genomic, transcriptomic, proteomic, metabolomic, neurophysiological and clinical data sets to reconstruct biological networks characteristic of normal and disease states. The magnitude, diversity, rich information content, and hierarchical connectivity of these data sets require the utilization and development of novel quantitative tools. The goal is to understand human disease at a molecular level in order to develop mechanism-based therapeutic interventions.
We invite applications for head of a new laboratory of Computational Medicine within the NEI Intramural Research Program. This initiative seeks to integrate and translate knowledge from genetics and biology to a wide range of disease processes using systems, network, statistical and bioinformatics approaches.
* Examples in ocular biology amenable to a systems approach would include neuro-immune interactions, gene regulatory networks during disease pathogenesis, protein interaction pathways, neuron-glial-vascular biological networks in the retina, neuronal networks in the CNS, and developmental conditions and disorders.
* The research program has interest in developing novel computational methodologies for analyzing large genetic, biological, biomedical, neuronal, and functional data sets. Particular attention will be paid to genotype-phenotype correlations, gene-gene and gene-environment interactions. In parallel, we will actively seek to develop disease intermediate phenotypes that reflect the underlying biology and pathophysiology of disease.
* Data sets from large clinical trials, genetic studies (including GWAS), expression profiling in normal and disease conditions, and from the eyeGENE human research repository for monogenic ophthalmic diseases will be developed to reconstruct and understand ocular biological networks that link genetic perturbations, small molecule interactions, and physiological processes, to predict normal and disease states
The NEI/NIH provides an exceptional environment of dedicated scientists as well as a wide range of resources. We currently envision that this program will be located in the newly constructed Porter Neuroscience complex that houses a diverse set of investigators from many different Institutes. The successful candidate will be expected to recruit tenure-track faculty in areas that may include computational medicine or neuroscience, network biology, genetic or molecular epidemiology, cell and molecular biology, statistical genetics, bioinformatics, and biostatistics into the new Laboratory of Computational Medicine. Applicants should have a MD, MD/PhD or PhD and an outstanding record of accomplishments in genetics, epidemiology, neuroscience, cell and molecular biology, biostatistics, or a related quantitative discipline. Senior scientists would have the opportunity to maintain their participation in existing collaborative research in non-eye diseases if desired.
This position will remain open until filled. Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments, names of three references, and a detailed experimental plan for the development of this program. These materials should be sent to: The Office of the Scientific Director, National Eye Institute, Attention: Ms. Mica Gordon (gordonmi@nei.nih.gov), NIH Building 31, 31 Center Drive, Room 6A22, Bethesda, MD, 20892. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor. DHHS and NIH are Equal Opportunity Employers.
Chief, Visuomotor Disorders Section
Laboratory of Sensorimotor Research, NEI
(Deadline: open-ended)
The National Eye Institute (NEI) seeks an outstanding clinician scientist for a tenured or tenure-track position as Chief, Visuomotor Disorders Section in the Laboratory of Sensorimotor Research (LSR) in the Division of Intramural Research. This recruitment is directed towards clinicians with expertise in central disorders that affect vision and/or eye movements (including disorders of binocular function). The post offers a unique opportunity for a talented individual to provide strong and stimulating leadership in an organization dedicated to uncovering new scientific knowledge, both laboratory and clinical. We welcome the full range of candidates at all levels.
The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements, visual perception and their disorders. The Visuomotor Disorders Section Chief is expected to create a vigorous research program dedicated to elucidating the role played by these brain mechanisms in human disease, and to explore treatments. The Chief will develop broad investigational plans, independently and in collaboration with other NEI investigators and research scientists in the United States and abroad. The Chief will examine and treat patients, as well as design, implement and conduct research and clinical protocols. An opportunity exists for the Section Chief to recruit staff and supervise training. The NEI provides an exceptional environment for clinical research including the infrastructure necessary for patient recruitment, a clinical protocol development group, and a Contract Research Organization that provides statistical and epidemiological expertise, data management and analysis, study monitoring, regulatory guidance, and overall operational support. The NIH Clinical Center provides additional access to exceptionally broad medical and diagnostic resources. In addition, the LSR provides exceptional support for more specialized needs, such as the measurement of eye movements and computational analysis/modeling.
The position requires an ability to integrate basic, clinical and translational research, and create an intellectual synergy and an environment for state-of-the art patient care for those suffering from visual dysfunction. At a minimum, candidates should have a Doctor of Medicine degree from a school in the U.S. or Canada approved by a recognized accrediting body in the year of the applicant's graduation, or a Doctor of Medicine or equivalent degree from a foreign medical school which provided education and medical knowledge substantially equivalent to accredited schools in the United States. Candidates should be Board-certified, board eligible or equivalent, have direct clinical experience. Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments and three reference letters. Applicants should also submit a written statement with their perspective on the needs and opportunities necessary to move from the basic understanding of brain mechanisms supporting vision and eye movements to clinical therapeutic interventions and improved patient care. This statement should indicate how the applicant's particular expertise and background could contribute to this transition. Applications should be sent to: Mica Gordon, Executive Assistant, Office of the Scientific Director, National Eye Institute, Building 31, Room 6A22, 31 Center Drive, Bethesda, MD 20892; Tel: 301-451-6763, Email: gordonmi@nei.nih.gov. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.
Posted by Kuan-Teh Jeang at 13:30 Comments (0)
Last year, for the first time, General Motors sold more cars in
The Keynote speaker for the ASBMB virology meeting will be Professor Michael MC Lai who is currently a distinguished investigator at Academia Sincia,
Ni hao! We encourage your participation at this meeting, and we look forward to seeing you July in
Posted by Kuan-Teh Jeang at 14:07 Comments (0)
Abstract submission form now available for the SCBA International Meeting July 25 -29, 2011
The 13th SCBA international conference www.SCBAmeeting2011.org in Guangzhou, China (July 25-29, 2011) is now accepting Abstract submissions. A word template for preparing your Abstract can be downloaded from this link. http://www.scbasociety.org/2011-Guangzhou/2011-SCBA-Abstract-form.doc
Completed Abstract forms can be uploaded at the following webpage after you click to choose an appropriate topic area. http://www.scbameeting2011.org/channel/submission.aspx
If you have questions, please email KT Jeang at ktjeang@yahoo.com for assistance.
Posted by Kuan-Teh Jeang at 22:25 Comments (0)