Chemistry Central Blog
Chemistry of Ageing: New thematic series for Chemistry Central Journal
We are pleased to announce a new thematic series for Chemistry Central Journal covering the Chemistry of Ageing.
Gerontology has traditionally been dominated by biological research groups. In recent years, the potential impact of chemical analysis and small molecule interventions has become widely recognised, and there are now a growing number of chemists undertaking ageing research. Research into ageing spans the full range chemistry. Advanced analytical and physical techniques are being used to observe age-related changes in living organisms. Equally, novel synthetic and medicinal chemistry is generating small molecule tools for the dissection of complex biological pathways, as well as potential life- and health-span extending therapeutics.
This thematic series, edited by Elizabeth Ostler from the University of Brighton, will cover:
- Glycation, oxidative stress and other degenerative processes
- Cellular senescence; mechanistic dissection and interventions
- Telomerase inhibitors and activators
- Small molecules with life-extending activity such as resveratrol and rapamycin
- Novel methods for mining complex cohort and life-course data
The first article in the series has already been published. In this study, Mark Bagley and colleagues at Cardiff University synthesised two diaminopyridine-based JNK inhibitors, and tested their effects on the proliferation and morphology of Werner syndrome fibroblasts in comparison to the widely used JNK inhibitor SP600125.
We welcome your contributions to this thematic series, and if you are interested in submitting a paper then please feel free to contact us for further information.
Posted by Bailey Fallon at 14:55 Comments (0)