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BioMed Central Blog

Friday Mar 12, 2010

Highlights from the latest issue of Arthritis Research & Therapy

In each print edition of Arthritis Research & Therapy the Editors-in-Chief, Profs Ravinder Maini and Peter Lipsky, highlight articles that are of special interest to the journal's readership – the Editors’ choice.

In the latest issue, a feasibility trial by Ng and colleagues found that a combination of glucosamine sulphate supplementation and walking for approximately 30 minutes a day, three times a week, significantly reduced pain and improved physical function in osteoarthritis patients.

Another selection by the Editors is a study by Schurgers et al which highlights the discrepancy between the in vitro and in vivo effects of mesenchymal stem cells.  The team of researchers from Katholieke Universiteit Leuven, Belgium, demonstrated that murine bone marrow-derived mesenchymal stem cells dose-dependently suppress T cell proliferation in vitro, but are unable to influence the disease course in a mouse model of collagen-induced arthritis.

Also making the Editors' choice is a comprehensive review article examining the contribution of genetic variation and infection to the pathogenesis of anti-neutrophil cytoplasmic antibody-associated systemic vasculitis, with a focus on the role of autoantibodies to the membrance protein LAMP-2.

All research published in Arthritis Research & Therapy is open access; reviews published within the previous 6 months require a subscription. Visit the journal website to view the latest articles published in the journal.

Abigail Jones

Senior Assistant Editor - Arthritis Research & Therapy


 

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